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Trimethylacetyl chloride, 98+%

CAS: 3282-30-2 | C5H9ClO | 120.58 g/mol

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Disclaimers: RUO – Research Use Only


Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.


Product Identifier
  • Trimethylacetyl chloride

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 2
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 1
  • Flammable liquid Category 2
  • Substances and mixtures corrosive to metals Category 1
  • Skin corrosion/irritation Category 1 B

Hazard Statement
  • H225- Highly flammable liquid and vapour.
  • H290- May be corrosive to metals.
  • H302- Harmful if swallowed.
  • H314- Causes severe skin burns and eye damage.
  • H318- Causes serious eye damage.
  • H330- Fatal if inhaled.

Precautionary Statement
  • P210- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280- Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331- IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353- IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310- Immediately call a POISON CENTER/doctor/.

Supplemental Information
  • MIXTURE LIST- Contains : Pivaloyl chloride