1. Home

Proteintech YAP1 Rabbit anti-Human, Mouse, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Additional Details:
Additional Details: Weight: 0.00010kg



Product Code. 16821874

Quantity Price
1 145.0  € / 20µL
In stock, ready to ship: 1
Add to basket


Description and Specification

Specification

Antigen YAP1
Applications Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Flow Cytometry,Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene YAP1
Gene Accession No. P46937, P46938, Q1L8J7
Gene Alias 65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog
Gene Symbols yap1
Host Species Rabbit
Immunogen YAP1 Fusion Protein Ag4510
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10413, 22601, 561411
Target Species Zebrafish,Human,Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG

YAP1 (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.